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  • Sunday, Aug 24th
    10:30 AM - 10:45 AM ET
    1A-01 - Comparative Effectiveness of GLP-1RA, SGLT2i, and DPP4i for New-Onset Cardiovascular Outcomes: A debiased Target Trial Emulation Study
    Location: 207AB
    Presenting Author: Bingyu Zhang – University of Pennsylvania
    Co-Author: Ting Zhou – University of Pennsylvania
    Co-Author: Huilin Tang – University of Pennsylvania
    Co-Author: Jiajie Chen – University of Pennsylvania
    Co-Author: Yiwen Lu – University of Pennsylvania
    Co-Author: Dazheng Zhang – University of Pennsylvania
    Co-Author: Tianchu Lyu – University of California, Irvine
    Co-Author: Kai Zheng – University of California, Irvine
    Co-Author: Yong Chen – University of Pennsylvania
    Drug Effectiveness
  • Sunday, Aug 24th
    10:45 AM - 11:00 AM ET
    1A-02 - SGLT2 Inhibitors, GLP-1 Receptor Agonists, and DPP4 Inhibitors and the Risk of Hypomagnesemia in Type 2 Diabetes: A Multi-Institutional Cohort Study with Target Trial Emulation
    Location: 207AB
    Presenting Author: Shih-Chieh Shao, PhD. – Population Health Data Center, National Cheng Kung University, Tainan, Taiwan
    Co-Author: Daniel Hsiang-Te Tsai – Population Health Data Center, National Cheng Kung University, Tainan, Taiwan
    Co-Author: Albert Tzu-Ming Chuang, PharmD – Population Health Data Center, National Cheng Kung University, Tainan, Taiwan
    Co-Author: Kuan-Hung Liu – Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    Co-Author: Edward Chia-Cheng Lai, PhD – Population Health Data Center, National Cheng Kung University
    Drug Effectiveness
  • Sunday, Aug 24th
    11:00 AM - 11:15 AM ET
    1A-03 - Primary Prevention of Cardiovascular and Renal Outcomes with GLP-1 Receptor Agonists in Adults with Obesity: A Target Trial Emulation Study
    Location: 207AB
    Presenting Author: Huilin Tang – University of Pennsylvania
    Co-Author: Bingyu Zhang – University of Pennsylvania
    Co-Author: Yiwen Lu – University of Pennsylvania
    Co-Author: Ting Zhou – University of Pennsylvania
    Co-Author: Dazheng Zhang – University of Pennsylvania
    Co-Author: Yong Chen – University of Pennsylvania
    Drug Effectiveness
  • Sunday, Aug 24th
    11:15 AM - 11:30 AM ET
    1A-04 - Comparative Effectiveness of Current Glucose-Lowering Medications in Type 2 Diabetes Mellitus: Emulation of a modified GRADE trial
    Location: 207AB
    Co-Author: Avik Ray, MD, MS – Brigham and Women's Hospital
    Presenting Author: Sushama Kattinakere Sreedhara, MBBS, MSPH – Brigham and Women's Hospital/Harvard Medical School
    Co-Author: Julie M. Paik, MD, ScD – Brigham and Women's Hospital
    Co-Author: Sara J. Cromer, MD – Massachusetts General Hospital
    Co-Author: Katsiaryna Bykov, PharmD, ScD – Brigham and Women's Hospital
    Co-Author: Georg Hahn, PhD – Brigham and Women's Hospital
    Co-Author: Robert Glynn – Brigham and Women's Hospital
    Co-Author: Deborah J. Wexler, MD, MSc – Massachusetts General Hospital
    Co-Author: Elisabetta Patorno, MD, DrPH – Brigham and Women's Hospital
    Drug Effectiveness
  • Sunday, Aug 24th
    11:30 AM - 11:45 AM ET
    1A-05 - End-stage renal diseases associated with the use of SGLT2 inhibitors versus GLP-1 receptor agonists among individuals with metabolic dysfunction-associated steatotic liver disease: A nationwide cohort study
    Location: 207AB
    Presenting Author: Hwa Yeon Ko, PharmD – School of Pharmacy, Sungkyunkwan University, Suwon, South Korea
    Co-Author: Bin Hong – School of Pharmacy, Sungkyunkwan University, Suwon, South Korea
    Co-Author: Sungho Bea, PharmD, PhD – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts
    Co-Author: Jae Hyun Bae – Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
    Co-Author: Young Min Cho – Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
    Co-Author: Yoosoo Chang, MD, PhD – Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Co-Author: Seungho Ryu – Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Co-Author: Christopher Byrne – National Institute for Health and Care Research, Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom
    Co-Author: Ju-Young Shin, PharmD, PhD – School of Pharmacy, Sungkyunkwan University, Suwon, South Korea
    Drug Effectiveness
  • Sunday, Aug 24th
    11:45 AM - 12:00 PM ET
    1A-06 - Evaluation of the safety of continuing vs. discontinuing pre-pregnancy chronic hypertension pharmacotherapy in pregnancy: a target trial emulation approach
    Location: 207AB
    Presenting Author: Catherine Psaras, PhD – University of California, San Diego
    Co-Author: Erin Delker, PhD – University of California, San Diego
    Co-Author: Gretchen Bandoli, PhD – University of California, San Diego
    Drug Effectiveness
  • Sunday, Aug 24th
    1:30 PM - 3:00 PM ET
    SW-1D - What are possible approaches when the active comparator new users design (ACNU) is not easily applicable?
    Location: Ballroom AB
    Co-Author: Tianze Jiao – Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida
    Presenting Author: Anouk Déruaz Luyet, PhD, MPH – Boehringer Ingelheim International GmbH
    Co-Author: Elisabetta Patorno, MD, DrPH – Brigham and Women's Hospital
    Co-Author: Xabier García de Albéniz – RTI Health Solutions
    Co-Author: Kristian B. Filion, PhD – McGill University
    Drug Effectiveness
  • Sunday, Aug 24th
    3:35 PM - 3:40 PM ET
    2D-02 - Estimating the Effect of a Discontinued Amyotrophic Lateral Sclerosis Treatment on Time-to-death Using Sequential Target Trial Emulation
    Co-Author: Queeny Ip – Komodo Health
    Presenting Author: Yuqin Wei – Komodo Health
    Co-Author: Ting-Ying Huang – Komodo Health
    Co-Author: Ahmed Noman – Komodo Health
    Co-Author: Kenneth A. Taylor, DPT, PhD – Komodo Health
    Drug Effectiveness
  • Sunday, Aug 24th
    5:15 PM - 6:45 PM ET
    SW-2A - Real-World Evidence in Regulatory Decision-Making for Medical Products
    Location: 206
    Presenting Author: Marie Bradley, PhD, MPharm, MSc.PH – RWE Analytics, CDER, Food and Drug Administration
    Co-Author: Gerald Dal Pan, MD, MHS – US Food and Drug Administration
    Co-Author: Richard A. Forshee – Office of Biostatistics and Pharmacovigilance, Center for Biologics Evaluation and Research
    Co-Author: Donna Rivera – Food and Drug Administration
    Co-Author: Daniel Canos, PhD – FDA CDRH OCEA
    Drug Effectiveness
  • Monday, Aug 25th
    8:15 AM - 8:30 AM ET
    3A-01 - Cardiovascular Effectiveness of Semaglutide: Using Real-World Data to Predict Findings of the Ongoing SOUL Cardiovascular Outcomes Trial
    Presenting Author: Sushama Kattinakere Sreedhara, MBBS, MSPH – Brigham and Women's Hospital/Harvard Medical School
    Co-Author: Sebastian Schneeweiss, MD, ScD – Brigham and Women's Hospital and Harvard Medical School
    Co-Author: Elyse C. DiCesare, BA – Brigham and Women's Hospital/Harvard Medical School
    Co-Author: Elisabetta Patorno, MD, DrPH – Brigham and Women's Hospital
    Co-Author: Marie Bradley, PhD, MPharm, MSc.PH – RWE Analytics, CDER, Food and Drug Administration
    Co-Author: John Concato – Yale University School of Medicine
    Co-Author: Shirley V. Wang – Brigham and Women's Hospital, Harvard Medical School
    Drug Effectiveness
  • Monday, Aug 25th
    8:30 AM - 8:45 AM ET
    3A-02 - Concomitant use of direct oral anticoagulants and COX-2 selective non-steroidal anti-inflammatory drugs and the risk of gastrointestinal bleeding in patients with non-valvular atrial fibrillation: multinational cohort study
    Presenting Author: Fabian M. Meinert – Charité - Universitätsmedizin Berlin
    Co-Author: Jenny Dimakos – McGill University
    Co-Author: Ying Cui – Lady Davis Institute
    Co-Author: Kristian B. Filion, PhD – McGill University
    Co-Author: Christel Renoux, MD, PhD – Department of Epidemiology, Biostatistics and Occupational Health, McGill University
    Co-Author: Antonios Douros – Universitätsmedizin Berlin
    Drug Effectiveness
  • Monday, Aug 25th
    8:45 AM - 9:00 AM ET
    3A-03 - The association between the use of RAAS inhibitors and prevention of new-onset pancreatic cancer: A target trial emulation
    Presenting Author: Fanxing Du – Department of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida
    Co-Author: Thomas D. Schmittgen – Department of Pharmaceutics, College of Pharmacy, University of Florida
    Co-Author: Yi Guo – University of Florida
    Co-Author: Farzin Khosrow-Khavar – Department of Biostatistics and Epidemiology, School of Public Health, Rutgers, The State University of New Jersey
    Co-Author: Qing Liu – Department of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida
    Co-Author: Corey M. Perkins – Department of Pharmaceutics, College of Pharmacy, University of Florida
    Co-Author: Jinmai Jiang – Department of Pharmaceutics, College of Pharmacy, University of Florida
    Co-Author: David Deremer – Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida
    Co-Author: Caitrin W. McDonough – Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida
    Co-Author: Yi Lian – Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania
    Co-Author: Thomas J. George – University of Florida
    Co-Author: Tianze Jiao – Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida
    Drug Effectiveness
  • Monday, Aug 25th
    9:00 AM - 9:15 AM ET
    3A-04 - Comparative Effectiveness of Denosumab and Oral Bisphosphonates in UK and Danish Real World Data
    Presenting Author: Eng Hooi (Cheryl) Tan – University of Oxford
    Co-Author: Trishna Rathod-Mistry – University of Oxford
    Co-Author: Victoria Strauss – Boehringer Ingelheim
    Co-Author: James O’Kelly – Amgen Ltd, Uxbridge, UK
    Co-Author: Vanessa Brunetti – Amgen Ltd, Uxbridge, UK
    Co-Author: Alma Becic Pedersen – Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
    Co-Author: Vera Ehrenstein, MPH, DSc – Department of Clinical Epidemiology and Center for Population Medicine, Aarhus University, Aarhus, Denmark
    Co-Author: Daniel Prieto-Alhambra – Health Data Sciences, Centre for Statistics in Medicine, University of Oxford
    Drug Effectiveness
  • Monday, Aug 25th
    9:15 AM - 9:30 AM ET
    3A-05 - Association between leukotriene receptor antagonist use and reduced risk of epileptic seizure in patients with asthma: a self-controlled case series study
    Presenting Author: Boqing Chen – School of Pharmacy, University College London
    Co-Author: Kenneth Man – School of Pharmacy, University College London
    Co-Author: Yogini Jani, PhD – UCLH-UCL Centre for Medicines Optimisation Research and Education, UCLH NHS Foundation Trust
    Co-Author: Wallis Lau, PhD – Research Department of Practice and Policy, School of Pharmacy, University College London, London
    Drug Effectiveness
  • Monday, Aug 25th
    9:30 AM - 9:45 AM ET
    3A-06 - Comparison of oral and long-acting injectable antipsychotics on disease relapses and healthcare utilizations in bipolar disorder: a 20-year follow-up study
    Presenting Author: Eunice Kehui Deng – Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Co-Author: Caige Huang – Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong Special Administrative Region, China
    Co-Author: Yue Wei – Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong Special Administrative Region, China
    Co-Author: Kit Wa Chan – the university of hong kong
    Co-Author: David J Castle – University of Tasmania
    Co-Author: Francisco Tsz Tsun Lai, PhD – The University of Hong Kong
    Co-Author: Wai Yin Chan – the university of hong kong
    Drug Effectiveness
  • Monday, Aug 25th
    9:30 AM - 9:45 AM ET
    3F-06 - Oral Anticoagulation and Risk of Adverse Clinical Outcomes in Patients with Venous Thromboembolism
    Presenting Author: Sungho Bea, PharmD, PhD – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts
    Co-Author: Geetha S Iyer, PhD – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts
    Co-Author: Dae Hyun Kim, MD, ScD – Harvard Medical School
    Co-Author: Kueiyu Joshua Lin, MD, ScD, MPH – Brigham and Women's Hospital and Harvard Medical School
    Co-Author: Yichi Zhang – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts
    Co-Author: Heidi Zakoul – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts
    Co-Author: Helen Tesfaye – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts
    Co-Author: Katsiaryna Bykov, PharmD, ScD – Brigham and Women's Hospital
    Drug Effectiveness
  • Tuesday, Aug 26th
    9:30 AM - 9:45 AM ET
    5F-05 - Effectiveness of Sarilumab vs. Methotrexate as a Glucocorticoid-sparing agent in Patients with Polymyalgia Rheumatica
    Presenting Author: Jeffrey R. Curtis – The University of Alabama at Birmingham, Birmingham, AL, USA
    Co-Author: Fenglong Xie – The University of Alabama at Birmingham, Birmingham, AL, USA
    Co-Author: Christian Dejaco – Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Medical University, Graz, Austria
    Co-Author: Kerri Ford – Sanofi, Cambridge, MA, USA
    Co-Author: Shanette R. Daigle – FASTER Medicine
    Co-Author: Sebastian E. Sattui – Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA
    Drug Effectiveness
  • Tuesday, Aug 26th
    10:30 AM - 12:00 PM ET
    SW-4A - Harnessing Real-world Evidence to Address Drug Shortages
    Location: 208AB
    Presenting Author: Adel Alrwisan – Saudi Food and Drug Authority
    Co-Author: Grace Chai – United States Food and Drug Administration
    Co-Author: Mina Tadrous, PhD – University of Toronto
    Co-Author: Tom Kraus
    Co-Author: Hisham Aljadhey
    Drug Effectiveness
  • Tuesday, Aug 26th
    10:30 AM - 12:00 PM ET
    SW-4B - Real-world evidence fit for regulatory applications — what does good look like?
    Location: 202AB
    Presenting Author: Joshua Gagne, PharmD, ScD, FISPE – Johnson & Johnson
    Co-Author: Heather M. Colvin, MPP – Johnson & Johnson Medtech
    Co-Author: Dan Riskin, MD, FACS – Verantos
    Co-Author: Dani Prieto-Alhambra – University of Oxford
    Co-Author: Marie Bradley, PhD, MPharm, MSc.PH – RWE Analytics, CDER, Food and Drug Administration
    Drug Effectiveness
  • Tuesday, Aug 26th
    1:30 PM - 1:45 PM ET
    6C-01 - Comparative Safety of Acetaminophen-Containing Hydrocodone versus Oxycodone among Adults with Cirrhosis
    Presenting Author: Kevin Pritchard – Brigham and Women's Hospital
    Co-Author: Kueiyu Joshua Lin, MD, ScD, MPH – Brigham and Women's Hospital and Harvard Medical School
    Co-Author: Tracey Simon – Massachusetts General Hospital
    Drug Effectiveness
  • Tuesday, Aug 26th
    2:00 PM - 2:15 PM ET
    6C-03 - Using Real-World Data to Predict Findings of an Ongoing Phase IV Trial: Glycemic Control of Semaglutide vs Standard of Care
    Presenting Author: Sushama Kattinakere Sreedhara, MBBS, MSPH – Brigham and Women's Hospital/Harvard Medical School
    Co-Author: Sebastian Schneeweiss, MD, ScD – Brigham and Women's Hospital and Harvard Medical School
    Co-Author: Elvira D'Andrea – Brigham and Women's Hospital/Harvard Medical School
    Co-Author: Janick Weberpals, RPh, PhD – AstraZeneca, R&D Oncology Data Science
    Co-Author: Elyse C. DiCesare, BA – Brigham and Women's Hospital/Harvard Medical School
    Co-Author: Elisabetta Patorno, MD, DrPH – Brigham and Women's Hospital
    Co-Author: Theodore Tsacogianis – Brigham and Women's Hospital/Harvard Medical School
    Co-Author: Marie Bradley, PhD, MPharm, MSc.PH – RWE Analytics, CDER, Food and Drug Administration
    Co-Author: John Concato – Yale University School of Medicine
    Co-Author: Shirley V. Wang – Brigham and Women's Hospital, Harvard Medical School
    Drug Effectiveness
  • Tuesday, Aug 26th
    2:15 PM - 2:30 PM ET
    6C-04 - Transporting the LEADER Study Results to VA Cohorts: Assessing Liraglutide's Impact on Cardiovascular Outcomes in a Veteran Population
    Presenting Author: Kevin Josey – University of Colorado Anschutz Medical Campus
    Co-Author: Wenhui Liu – Rocky Mountain VA Medical Center
    Co-Author: Morten Medici – Novo Nordisk A/S
    Co-Author: Cole Hoffman – University of Colorado Anschutz Medical Campus
    Co-Author: Debashis Ghosh – University of Colorado Anschutz Medical Campus
    Co-Author: Sridharan Raghavan – Rocky Mountain VA Medical Center
    Drug Effectiveness
  • Tuesday, Aug 26th
    2:30 PM - 2:45 PM ET
    6C-05 - Aspirin use and the risk of hepatic events in patients with metabolic dysfunction-associated steatotic liver disease: A target trial emulation with clone-censor-weight approach
    Presenting Author: Hwa Yeon Ko, PharmD – School of Pharmacy, Sungkyunkwan University, Suwon, South Korea
    Co-Author: Yoosoo Chang, MD, PhD – Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Co-Author: Seungho Ryu – Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    Co-Author: Ju-Young Shin, PharmD, PhD – School of Pharmacy, Sungkyunkwan University, Suwon, South Korea
    Drug Effectiveness
  • Tuesday, Aug 26th
    2:45 PM - 3:00 PM ET
    6C-06 - Real-World Radium-223 Utilization Patterns and Survival in Older Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC): A SEER Registry-Linked Medicare Database
    Presenting Author: Bo Zhou – University of North Texas Health Science Center
    Co-Author: Amit Raval – Bayer HealthCare Pharmaceuticals
    Co-Author: Yifan Zhang – University of North Texas Health Science Center
    Co-Author: Nethra Sambamoorthi – University of North Texas Health Science Center
    Co-Author: Matthew Korn – Bayer HealthCare Pharmaceuticals
    Co-Author: Niculae Constantinovici – Bayer Consumer Care
    Co-Author: Rana McKay – University of California, San Diego
    Co-Author: Usha Sambamoorthi – University of North Texas Health Science Center
    Drug Effectiveness